CHIMIA 9/2006, Vol. 60

Process Chemistry 2006 09

Scientific Content

All articles of this issue are available on Ingenta.

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Additional content

Contents

514

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Editorial

516

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518

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Icon ExternalLinkEarly Process Development: The Wyeth Approach
M.K. O’Brien*, M. Kolb*, K. Sutherland, K. McCoy, A. Pilcher 

 

523

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Process Development for Active Pharmaceutical Ingredients Following a Developmental Cascade
C. Adler, J. Brunner, C. Fichtner, P. Küng, M.K. Levis, H.-R. Ruchti, A. Sjöberg, B. Weber* 

 

530

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Process Development and Production Concepts for the Manufacturing of Organic Fine Chemicals at LONZA
G. Heckmann, F. Previdoli, T. Riedel, D. Ruppen, D. Veghini*, U. Zacher 

 

534

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543

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554

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Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate
B.M. Andresen, S. Caron, M. Couturier*, K.M. DeVries, N.M. Do, K. Dupont-Gaudet, A. Ghosh*, M. Girardin, J.M. Hawkins, T.M. Makowski, M. Riou, J.E. Sieser, J.L. Tucker, B.C. Vanderplas, T.J.N. Watson 

 

561

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With Asymmetric Hydrogenation Towards a New, Enantioselective Synthesis of Orlistat
R. Birk, M. Karpf, K. Püntener*, M. Scalone, M. Schwindt, U. Zutter 

 

566

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Icon ExternalLinkThe Formation of a Crystalline Oxazolidin-5-one from (l)-Alanine and its Use as a Chiral Template in the Practical Synthesis of α-Substituted Alanine Esters
M. Eriksson*, E. Napolitano, J. Xu, S. Kapadia, D. Byrne, L. Nummy, N. Grinberg, S. Shen, H. Lee, V. Farina 

 

574

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Recent Optimization Highlights of the Georgywood Process
J.-P. Barras, B. Bourdin, F. Schröder* 

 

580

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584

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Icon ExternalLinkThe Chemical Development of CHIR-258
S. Zhu*, E. Harwood, S. Cai, X. Shang, G. Galvin, L. Jin, A. Yeung, B. Diaz, M. Zheng, D. Ryckman 

 

593

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An Improved Process for Repaglinide via an Efficient and One Pot Process of (1S)-3-methyl-1- (2-piperidin-1-ylphenyl)butan-1-amine – A Useful Intermediate
N. Kolla, C.R. Elati, P.J. Vankawala, S. Gangula, E. Sajja, Y. Anjaneyulu, A. Bhattacharya, V. Sundaram, V.T. Mathad* 

 

598

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605

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611

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Cost Analysis of a Commercial Manufacturing Process of a Fine Chemical Compound using Micro Process Engineering
U. Krtschil, V. Hessel*, D. Kralisch, G. Kreisel, M. Küpper, R. Schenk 

 

618

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Continuous Chemistry in Microreaction Systems for Practical Use
G. Müller, T. Gaupp, F. Wahl, G. Wille* 

 

623

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628

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631

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Icon ExternalLinkUsing Bacteria to Quantify Arsenic Contamination in Potable Water
J.R. van der Meer*, M. Berg, P.T.K. Trang 

SCG/SSC/SCS

633

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Information

634

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CHIMIA-Report

636

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Icon OpenAccessContent Open Access Content
Icon SubscribedContent Subscribed Content. To access the articles you must be a SCS member or a CHIMIA subscriber.

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