Vol. 71 No. 10 (2017): Medicinal Chemistry

Editorial

• Medicinal Chemistry Editorial

  Guido Koch

  643

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Scientific Articles

• Drugs from the Oceans: Marine Natural Products as Leads for Drug Discovery

  Karl-Heinz Altmann

  646

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• Exploring Natural Product Fragments for Drug and Probe Discovery

  Axel Pahl, Herbert Waldmann, Kamal Kumar

  653

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• Chemical Space: Big Data Challenge for Molecular Diversity

  Mahendra Awale, Ricardo Visini, Daniel Probst, Josep Arús-Pous, Jean-Louis Reymond

  661

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• The Screening Compound Collection: A Key Asset for Drug Discovery

  Christoph Boss, Julien Hazemann, Thierry Kimmerlin, Modest von Korff, Urs Lüthi, Oliver Peter, Thomas Sander, Romain Siegrist

  667

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• Design, Properties and Recent Application of Macrocycles in Medicinal Chemistry

  Philipp Ermert

  678

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• Following the Lead from Nature with Covalent Inhibitors

  Roman Lagoutte, Nicolas Winssinger

  703

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• Targeted Delivery of Cytotoxic Drugs: Challenges, Opportunities and New Developments

  Samuele Cazzamalli, Alberto Dal Corso, Dario Neri

  712

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• Discovery of Potent and Selective p53-MDM2 Protein–Protein Interaction Inhibitors as Anticancer Drugs

  Philipp Holzer

  716

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• Milestones to the Discovery of T-type Calcium Channel Blockers for the Treatment of Generalized Epilepsies

  Olivier Bezençon, Thomas Pfeifer, Johannes Mosbacher, Isabelle Reymond, Eric A. Ertel, Ruben de Kanter, Bruno Capeleto, Elvire Fournier, Markus Rey, Luca Moccia, Michael Toeroek-Schafroth, René Roscher, Richard Moon, John Gatfield, Melanie Kessler, Romain Siegrist, Bibia Heidmann, Davide Pozzi, Simon Stamm, Luboš Remeň, Sylvia Richard, Lloyd Simons, Rick Gaston, Dennis Downing, Corinna Grisostomi, Catherine Roch, Benno Schindelholz

  722

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Note

• Top 200 Drugs by Worldwide Sales 2016

  Gottfried Sedelmeier, Joerg Sedelmeier

  730

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Columns, Conference Reports

• Swiss Science Concentrates

  Caroline D. Bösch, Mariusz Kownacki, Yuliia Vyborna, Simon M. Langenegger, Robert Häner

  731

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• Mineral Oil in Food – The Development of an Issue Highlights of Analytical Sciences in Switzerland

  Koni Grob

  732

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• Polymers with Exceptional Photoluminescence by Homoconjugation Polymer and Colloid Highlights

  Andreas Braendle, Aleksandr Perevedentsev, Nathan J. Cheetham, Paul N. Stavrinou, Jörg A. Schachner, Nadia C. Mösch-Zanetti, Markus Niederberger, Walter Caseri

  733

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• Production of a Recombinant Catechol 2,3-Dioxygenase for the Degradation of Micropollutants FH-HES Universities of Applied Sciences

  Domenico Celesia, Isabelle Salzmann, Emanuel Vaz Porto, Floriane Walter, Cindy Weber, Rémy Dufresne, Simon Crelier

  734

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• BioTech 2017 Conference Report, Wädenswil, 7./8.9.2017 Conference Report

  Caspar Demuth

  739

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Community News

• Community News

  740

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Events

• Congresses, Symposia, Lectures, Education Courses

  744

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• Impressum

  748

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CHIMIA Report/Company News

• CHIMIA Report/Company News Companies present themselves and their products

  749

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