Vol. 58 No. 9 (2004): Pharmaceutical Industry in Switzerland

Editorial

Editorial Editorial

Reto Naef

576
- PDF

Scientific Articles

Molecular Informatics as an Enabling in silico Technology Platform for Drug Discovery

Edgar Jacoby, Ansgar Schuffenhauer, Maxim Popov, Kamal Azzaoui, Eric Vangrevelinghe, John Priestle, Philippe Ferrara, Bernard Faller, Pierre Acklin

577
- PDF
SpeedScreen, a Label-Free, Affinity-Based High-Throughput Screening Technology for the Discovery of Orphan Protein Ligands

Ireos Filipuzzi

585
- PDF
Lead Generation: Sowing the Seeds for Future Success

Konrad H. Bleicher, Matthias Nettekoven, Jens-Uwe Peters, René Wyler

588
- PDF
Small Molecule Drug Discovery in the Fast-Changing World of Biotechnology

Serge Halazy, Matthias K. Schwarz

601
- PDF
Drug Discovery in Oncology

Carlos García-Echeverría

608
- PDF
5-HT2C Receptor Agonists for the Treatment of Obesity. Biological and Chemical Adventures

David Adams, Sven Taylor, Stephan Röver, Hans Richter, Jean-Marc Plancher, Jacques Mizrahi, Craig S. Malcolm, Antony R. Knight, Guy A. Kennett, Paul Hebeisen, Ian A. Cliffe, Anne Bourson, Caterina Bissantz, Jon M. Bentley, Mike J. Bickerdike, Agnès Bénardeau, Steven P. Vickers

613
- PDF
The Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu®): A Challenge for Synthesis & Process Research

Stefan Abrecht, Peter Harrington, Hans Iding, Martin Karpf, René Trussardi, Beat Wirz, Ulrich Zutter

621
- PDF
2-Styryl-pyridines and 2-(3,4-Dihydro-naphthalen-2-yl)pyridines as Potent NR1/2B Subtype Selective NMDA Receptor Antagonists

Bernd Buettelmann, Alexander Alanine, Anne Bourson, Ramanjit Gill, Marie-Paule Heitz, Vincent Mutel, Emmanuel Pinard, Gerhard Trube, René Wyler

630
- PDF
Inhibitors of Plasmepsin II – Potential Antimalarial Agents

Christoph Boss, Reto Brun, Walter Fischli, Christoph Binkert, Solange Meyer, Lars Prade, Luke Harris, Lionel Coppex, Corinna Grisostomi, Olivier Corminboeuf, Jean-Marc Bourgeois, Rocco Furnari, Sylvia Richard-Bildstein, Thomas Weller

634
- PDF
Broad Spectrum Chemistry as Practised by Novartis Process Research

Stuart J. Mickel, Reto Fischer, Wolfgang Marterer

640
- PDF
Increased Productivity through Dynamic Process Optimization in Sterile Facility 303 at Novartis Pharma Stein AG

Peter Nyfeler, Antonio Zeoli, Cédric Bokalota, Roland Chatelain

649
- PDF

Columns, Conference Reports

Abschied von der Abteilung Chemie in Burgdorf: Offener Brief an alle Burgdorfer Chemikerinnen und Chemiker FH - HES

Ruth Weber

661
- PDF

Community News

Preisausschreibung - Mise au concours

663
- PDF
Var. Informations

664
- PDF

Events

Lectures, Congresses – Conferences – Workshops

666
- PDF

CHIMIA Report/Company News

CHIMIA-Report, 2004/09

667
- PDF

Vol. 58 No. 9 (2004): Pharmaceutical Industry in Switzerland

Editorial

Editorial Editorial

Scientific Articles

Molecular Informatics as an Enabling in silico Technology Platform for Drug Discovery

SpeedScreen, a Label-Free, Affinity-Based High-Throughput Screening Technology for the Discovery of Orphan Protein Ligands

Lead Generation: Sowing the Seeds for Future Success

Small Molecule Drug Discovery in the Fast-Changing World of Biotechnology

Drug Discovery in Oncology

5-HT2C Receptor Agonists for the Treatment of Obesity. Biological and Chemical Adventures

The Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu®): A Challenge for Synthesis & Process Research

2-Styryl-pyridines and 2-(3,4-Dihydro-naphthalen-2-yl)pyridines as Potent NR1/2B Subtype Selective NMDA Receptor Antagonists

Inhibitors of Plasmepsin II – Potential Antimalarial Agents

Broad Spectrum Chemistry as Practised by Novartis Process Research

Increased Productivity through Dynamic Process Optimization in Sterile Facility 303 at Novartis Pharma Stein AG

Columns, Conference Reports

Abschied von der Abteilung Chemie in Burgdorf: Offener Brief an alle Burgdorfer Chemikerinnen und Chemiker FH - HES

Community News

Preisausschreibung - Mise au concours

Var. Informations

Events

Lectures, Congresses – Conferences – Workshops

CHIMIA Report/Company News

CHIMIA-Report, 2004/09

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