Vol. 54 No. 11 (2000): Pharmaceutical Chemistry

Editorial

Pharmaceutical Chemistry Editorial

Gerd Folkers

611
- PDF

Scientific Articles

Epothilones and Their Analogs – Potential New Weapons in the Fight Against Cancer

Karl-Heinz Altmann, Guido Bold, Giorgio Caravatti, Nicole End, Andreas Flörsheimer, Vito Guagnano, Terence O'Reilly, Markus Wartmann

612
- PDF
Functional Brain Receptor Imaging with Positron Emission Tomography

Simon M. Ametamey, Gerrit Westera, Pascale Gucker, Roland Schönbächler, Michael Honer, Jörg E. Spang, P. August Schubiger

622
- PDF
Using Structural Information of Peptides, Derived from NMR Spectroscopy, in Pharmaceutical Chemistry

Reto Bader, Mirjam Lerch, Gerd Folkers, Oliver Zerbe

627
- PDF
Molecular Recognition with Biological Receptors: Structure-Based Design of Thrombin Inhibitors

Patrick Betschmann, Christian Lerner, Stefan Sahli, Ulrike Obst, François Diederich

633
- PDF
CAFCA: a Novel Tool for the Calculation of Amphiphilic Properties of Charged Drug Molecules

Holger Fischer, Manfred Kansy, Daniel Bur

640
- PDF
The Influence of Oxygen and Nitrogen on the Radiolysis of Chloramphenicol

Philip Horsch, Hansruedi Altorfer

646
- PDF
Search for New Lead Compounds from Higher Plants

Kurt Hostettmann, Christian Terreaux

652
- PDF
Synergistic Use of Virtual Screening and Biophysical Methods for the Protein-Based Design of Peptidomimetics

Didier Rognan, Caterina Bissantz, Séverine Dédier, Antoine Logean, Stefan Reinelt

658
- PDF
Extended Substrate Acceptance of Herpes Simplex Virus Type 1 Thymidine Kinase: a New Chance for Gene and Antiviral Therapy

Leonardo Scapozza, Patrick Ballmer, Regula Johner, Remo Perozzo, Beatrice Pilger, Pavel Pospisil, Andrea Prota, Pierre Schelling, Loredana Spadola, Christine Wurth, Gerd Folkers

663
- PDF
Structure-Activity Relationships of Substituted 2,3,4,4a,5,10b-Hexahydro-benz[h]isoquinoline-6(1H)-ones as 5-HT2C Receptor Antagonists

Heinz Stadler, Jürgen Wichmann, Andrew J. Sleight, Michael Bös

669
- PDF
Lipophilicity and Related Molecular Properties as Determinants of Pharmacokinetic Behaviour

Bernard Testa, Giulia Caron, Patrizia Crivori, Sébastien Rey, Marianne Reist, Pierre Alain Carrupt

672
- PDF
A Strategy for the Identification of Differentially Expressed Proteins Secreted by Fibroblasts

Francesca Viti, Maja A. Bumke, Michela Silacci, Luciano Zardi, Dario Neri

678
- PDF
Radiopharmaceuticals for Targeted Tumor Diagnosis and Therapy

Robert Waibel, Ilse Novak-Hofer, Roger Schibli, Peter Bläuenstein, Elisa Garcia-Garayoa, Rolf Schwarzbach, Kurt Zimmermann, Raimo Pellikka, Olga Gasser, Alain Blanc, Matthias Brühlmeier, P. August Schubiger

683
- PDF

Columns, Conference Reports

L'ingénieur en génie chimique: du pilote au projet Engineers in Chemical Engineering: From Pilot to Project

Anne Dimitrov-Wagenknecht, Edmond Goy

689
- PDF

CHIMIA Report/Company News

CHIMIA-Report Companies present themselves and their products

A699
- PDF

Vol. 54 No. 11 (2000): Pharmaceutical Chemistry

Editorial

Pharmaceutical Chemistry Editorial

Scientific Articles

Epothilones and Their Analogs – Potential New Weapons in the Fight Against Cancer

Functional Brain Receptor Imaging with Positron Emission Tomography

Using Structural Information of Peptides, Derived from NMR Spectroscopy, in Pharmaceutical Chemistry

Molecular Recognition with Biological Receptors: Structure-Based Design of Thrombin Inhibitors

CAFCA: a Novel Tool for the Calculation of Amphiphilic Properties of Charged Drug Molecules

The Influence of Oxygen and Nitrogen on the Radiolysis of Chloramphenicol

Search for New Lead Compounds from Higher Plants

Synergistic Use of Virtual Screening and Biophysical Methods for the Protein-Based Design of Peptidomimetics

Extended Substrate Acceptance of Herpes Simplex Virus Type 1 Thymidine Kinase: a New Chance for Gene and Antiviral Therapy

Structure-Activity Relationships of Substituted 2,3,4,4a,5,10b-Hexahydro-benz[h]isoquinoline-6(1H)-ones as 5-HT2C Receptor Antagonists

Lipophilicity and Related Molecular Properties as Determinants of Pharmacokinetic Behaviour

A Strategy for the Identification of Differentially Expressed Proteins Secreted by Fibroblasts

Radiopharmaceuticals for Targeted Tumor Diagnosis and Therapy

Columns, Conference Reports

L'ingénieur en génie chimique: du pilote au projet Engineers in Chemical Engineering: From Pilot to Project

CHIMIA Report/Company News

CHIMIA-Report Companies present themselves and their products

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