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2024-10-25

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Current Issue

Vol. 79 No. 3 (2025): Innovation through Chemical Biology

CHIMIA Vol. 79 No. 3 (2025): Innovation through Chemical Biology

This CHIMIA issue on Innovation through Chemical Biology celebrates 2024 as an outstanding year for Chemical Biology in Switzerland. Numerous events took place throughout the year: DMCCB Symposium, Swiss Summer School in Chemical Biology, Peptide Therapeutics Forum, SCS-Syngenta Symposium and the EFMC International Symposium on Chemical Biology. In this issue we bring together some highlights in Chemical Biology from these various events.

Published: 2025-03-26

Editorial

Editorial

Vlad Pascanu, Amandine Kolleth

125
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Scientific Articles

Control of Therapeutic Activity through Programmed Assembly

Millicent Dockerill, Nicolas Winssinger

128-136
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Recent Advances in CBP/EP300 Degraders

Leonardo Palaferri , Iván Cheng-Sánchez, Cristina Nevado

137-145
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Precision Probing of O-GalNAc Glycosylation Using Bump-and-Hole Engineering

Abdul Zafar, Benjamin Schumann

146-151
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Reversible Covalent Reactions of Aldehydes and Salicylaldehydes Using a Lysine-Model Substrate

Cécile Delmas, Emine Sager, Chrystele Henry, Ulrich Hassiepen, Philip R. Skaanderup, Isabel Kerschgens

152-157
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Challenges and Opportunities in DNA Encoded Library Screens

Basilius Sauter, Pinwen Cai, Koder Dagher, Chiara Disraeli, Athira Kakkolliyil Prakash, Lukas Schneider, Angel Cores Esperon, Dennis Gillingham

158-161
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Towards the Rational Design of Monovalent Degraders: Lessons Learnt from Cyclin K Degraders

Katie L. Thomas, Benjamin R. Bellenie, Olivia W. Rossanese

162-166
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Oligonucleotide-based PROTACs to Degrade RNA- and DNA-Binding Proteins

Céline N. Weller, Jonathan Hall

167-171
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Columns, Conference Reports

Swiss Science Concentrates

Cesare Berton, Jonas Genz, Stanislav Prytuliak, Fan Liu, Eda Nisli, Deborah Bäcker, Perle Hermant, Samy Kichou, Ben Boback, Dominik Ernst, Tiago Rosa de Araujo, Henrik Braband, Jason P. Holland

172-173
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Learning Chemical Intuition: From Molecular Models to Neural Networks Chemical Education

Magdalena Lederbauer

174-175
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Flow Chemistry Highlights An Interview with Prof. Roger Marti

Christophe Allemann, Claudio Battilocchio

176
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7^th SCS - Syngenta Symposium 2024 'Unlocking Innovation through Chemical Biology'

Vlad Pascanu, Amandine Kolleth, Nina Declas, Nikolas Huwyler, Simone Berardozzi, Thomas Rossolini, Federico Dapiaggi

177-179
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Swiss Snow Symposium 2025 - Chemistry on Top of the Mountains!

Helena Solé-Àvila, Marta Oggloni, Konstantina K. Armadorou, Marie-Désirée Schlemper-Scheldt

180-181
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PCC Christmas Symposium Basel 2024

Pieter Brongers, Tzu-Chin Chang Chien, Elinor Morris, Ilse Friedländer, Richard Karl, Salome L. Heim, Elizaveta Maksimova, Livia Müller, Andreas Ostertag, Carlotta Seno, Benjamin Vermeer, Chiara Disraeli, Minqi Pan, Anies Rösch, Stephan Schumann, Luise Sokoliuk, Dorothee Wagner, Joël Wellauer, Amine Yücekul

182-183
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Community News

Community News

184-185
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Events

Events

186-191
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Impressum

192
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International Journal for Chemistry and Official Membership Journal of the Swiss Chemical Society (SCS) and its Divisions

CHIMIA, a scientific journal for chemistry in the broadest sense covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.