@article{Lathrop_Kim_Movassaghi_2012, title={Radical-mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids}, volume={66}, url={https://www.chimia.ch/chimia/article/view/2012_389}, DOI={10.2533/chimia.2012.389}, abstractNote={ Concise and general strategies for radical-based dimerization of cyclotryptamine and cyclotryptophan derivatives in addition to radical-based oxidation of structurally complex diketopiperazines are discussed. The impact of these radical-based chemistries on the rapid generation of molecular complexity is highlighted using representative examples from recent complex homodimeric alkaloid total syntheses. Additionally, a new and general strategy for radical-based directed heterodimerization of cyclotryptamine substructures via solvent-caged unsymmetrical diazene fragmentation is discussed. }, number={6}, journal={CHIMIA}, author={Lathrop, Stephen P. and Kim, Justin and Movassaghi, Mohammad}, year={2012}, month={Jun.}, pages={389} }