@article{Nakanishi_Katayev_Besnard_Kündig_2012, title={Palladium-NHC Catalyzed Enantioselective Synthesis of Fused Indolines via Inert C(sp3)-H Activation}, volume={66}, url={https://www.chimia.ch/chimia/article/view/2012_241}, DOI={10.2533/chimia.2012.241}, abstractNote={ New sterically hindered chiral N-heterocyclic carbene (NHC) ligands were used in palladium catalysis to bring about a highly enantioselective C(sp3)-H activation on the methylene site of a cycloalkane moiety. The intramolecular coupling reaction of a prochiral N-aryl-N-cycloalkyl methyl carbamate required high temperatures (140–160 °C) and afforded highly enantioenriched trans-2,3-fused indolines. }, number={4}, journal={CHIMIA}, author={Nakanishi, Masafumi and Katayev, Dmitry and Besnard, Céline and Kündig, E. Peter}, year={2012}, month={Apr.}, pages={241} }