Fluorotetrahydroquinolines from Diethyl 2-Fluoromalonate Ester

Authors

  • Craig A. Fisher Department of Chemistry Durham University, South Road Durham, DH1 3LE, UK
  • Antal Harsanyi Department of Chemistry Durham University, South Road Durham, DH1 3LE, UK
  • Graham Sandford Department of Chemistry Durham University, South Road Durham, DH1 3LE, UK. Graham.Sandford@durham.ac.uk
  • Dmitri S. Yufit Chemical Crystallography Durham University, UK
  • Judith A. K. Howard Chemical Crystallography Durham University, UK

DOI:

https://doi.org/10.2533/chimia.2014.425

Keywords:

Fluorinated heterocycle, Fluoromalonate, Fluorotetrahydroquinoline, Organofluorine chemistry, Selective fluorination

Abstract

A short series of fluorotetrahydroquinolines was synthesised in two steps from diethyl fluoromalonate and appropriate ortho-nitrobenzyl bromide precursors.

Downloads

Published

2014-06-26

Issue

Section

Scientific Articles