The Life Sciences Mass Spectrometry Research Unit

Authors

  • Gérard Hopfgartner School of Pharmaceutical Sciences University of Geneva, University of Lausanne Life Sciences Mass Spectrometry Quai Ernest-Ansermet, 30 CH-1211 Geneva 4, Switzerland. Gerard.Hopfgartner@unige.ch
  • Emmanuel Varesio School of Pharmaceutical Sciences University of Geneva, University of Lausanne Life Sciences Mass Spectrometry Quai Ernest-Ansermet, 30 CH-1211 Geneva 4, Switzerland

DOI:

https://doi.org/10.2533/chimia.2012.335

Keywords:

Mass spectrometry

Abstract

The Life Sciences Mass Spectrometry (LSMS) research unit focuses on the development of novel analytical workflows based on innovative mass spectrometric and software tools for the analysis of low molecular weight compounds, peptides and proteins in complex biological matrices. The present article summarizes some of the recent work of the unit: i) the application of matrix-assisted laser desorption/ionization (MALDI) for mass spectrometry imaging (MSI) of drug of abuse in hair, ii) the use of high resolution mass spectrometry for simultaneous qualitative/quantitative analysis in drug metabolism and metabolomics, and iii) the absolute quantitation of proteins by mass spectrometry using the selected reaction monitoring mode.

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Published

2012-05-30

Issue

Section

Scientific Articles