Bimorpholines as Alternative Organocatalysts in Asymmetric Aldol Reactions
DOI:
https://doi.org/10.2533/chimia.2007.232Keywords:
Aldol condensation, Bimorpholine, Organocatalysis, StereoselectiveAbstract
Asymmetric organocatalytic aldol condensation is discussed on the basis of intramolecular and inter-molecular reactions. In addition to the widely used proline and its derivatives an application of the new type of the organocatalyst – bimorpholines in the above-mentioned reactions is described. The new catalyst has a unique C2-symmetric skeleton with four acceptor sites that makes it stereoselective and efficient. Small changes in the structure of the catalyst lead to a remarkable loss of selectivity.Downloads
Published
2007-05-30
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Scientific Articles
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Copyright (c) 2007 Swiss Chemical Society
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
[1]
Chimia 2007, 61, 232, DOI: 10.2533/chimia.2007.232.