In-Strand Metallated Nucleic Acids – Novel Bioinorganic Constructs

Authors

  • Edwin C. Constable
  • Valérie Chaurin
  • Catherine E. Housecroft
  • Amina Wirth

DOI:

https://doi.org/10.2533/000942905777675660

Keywords:

Antisense, Dna, Oligopyridine, Rna, Ruthenium

Abstract

Synthetic strategies have been developed for the preparation of in-chain metallated oligonucleotides, in which the oligonucleotide sequence is interrupted by a metal-containing motif. In our work, oligopyridine metal-binding domains are used and approaches are outlined using both labile and non-labile metal centres.

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Published

2005-11-01

Issue

Section

Scientific Articles

How to Cite

[1]
E. C. Constable, V. Chaurin, C. E. Housecroft, A. Wirth, Chimia 2005, 59, 832, DOI: 10.2533/000942905777675660.