Development of Enzymes for Chemoenzymatic Synthesis

Abstract

With various recombinant DNA and protein engineering techniques now available, enzyme-based technologies are emerging as practical and environmentally acceptable methods for the synthesis of chiral intermediates and complex bioactive molecules. While enzyme technology offers a new opportunity in the chemical and pharmaceutical industries, development of novel and useful enzyme-catalyzed transformations not easily attainable otherwise for large-scale processes remains to be a challenge in the field.