Skeletal Editing of Heterocycles – A New Tool for Lead Exploration?

Medicinal Chemistry and Chemical Biology Highlights

Authors

  • Simon R. Williams Syngenta Crop Protection AG, Schaffhauserstrasse 101, CH-4332 Stein.
  • Julien C. Vantourout Syngenta Crop Protection AG, Schaffhauserstrasse 101, CH-4332 Stein.

DOI:

https://doi.org/10.2533/chimia.2024.446

Keywords:

Heterocyclic chemistry, Lead Exploration, Medicinal chemistry, Skeletal editing, Synthesis

Abstract

Many new methods for single atom skeletal editing of heterocycles have been developed in the past few years with obvious applications to discovery chemistry. In this perspective, we assess the recent advances in this field and the potential application to lead exploration campaigns.

CHIMIA Vol. 78 No. 6 (2024): Sustainable Development Goals in Chemistry in Switzerland

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Published

2024-06-26

Issue

Vol. 78 No. 6 (2024): Sustainable Development Goals in Chemistry in Switzerland

Section

Columns, Conference Reports

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License

Copyright (c) 2024 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
S. R. Williams, J. C. Vantourout, Chimia 2024, 78, 446, DOI: 10.2533/chimia.2024.446.