Understanding Intrinsic Warhead Reactivity and Cysteine Druggability in Covalent Drug Discovery: Medicinal Chemistry and Chemical Biology Highlights

Understanding Intrinsic Warhead Reactivity and Cysteine Druggability in Covalent Drug Discovery

Chiara Borsari Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milano, Italy https://orcid.org/0000-0002-4688-8362
Alexandra Ioana Corfu Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milano, Italy https://orcid.org/0009-0001-6733-1459
Paola Conti Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milano, Italy https://orcid.org/0000-0003-2140-0567

Covalent inhibitors, Druggable cysteines, Intrinsic reactivity, Rational Design, Warhead

2023-05-31

Columns, Conference Reports

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Chimia 2023, 77, 349, DOI: 10.2533/chimia.2023.349.

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