The Evolution of Flow Chemistry: An Opinion on Factors Driving Innovation

Authors

  • Samuel L. Bourne CARBOGEN AMCIS AG, Neulandweg 5, CH-5502 Hunzenschwil
  • Franz Amann CARBOGEN AMCIS AG, Neulandweg 5, CH-5502 Hunzenschwil
  • Steven V. Ley Yusuf Hamied Department of Chemistry University of Cambridge, Lensfield Road, Cambridge, CB21EW https://orcid.org/0000-0002-7816-0042

DOI:

https://doi.org/10.2533/chimia.2023.288

PMID:

38047823

Keywords:

Continuous processing, Drug substance, Flow chemistry, R&D efficiency, Scientific progress

Abstract

This article seeks to provide an overview of the environmental factors within the pharmaceutical industry that have contributed to the emergence of flow chemistry over the past two decades. It highlights some of the challenges facing the industry and describes how they are being overcome by the exponential trajectory of scientific progress in the area. We identify current trends and offer a speculative glimpse into the future of drug development and manufacturing with some examples of progress being made at CARBOGEN AMCIS.

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Published

2023-05-31

Issue

Vol. 77 No. 5 (2023): The Evolution of Flow Chemistry

Section

Scientific Articles

License

Copyright (c) 2023 S. L. Bourne, F. Amann, S. V. Ley

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
S. L. Bourne, F. Amann, S. V. Ley, Chimia 2023, 77, 288, DOI: 10.2533/chimia.2023.288.