Hyperpolarized Solvatochromic Nanosensors towards Heparin Sensing in Blood
Keywords:Agarose, Heparin, Nanoparticles, Protamine, Solvatochromism
Heparin quantification at the point of care has been of medical interest for years but a suitable point of care measurement method for whole blood is still elusive. Our group has recently developed a nanoparticle-based optical sensor for protamine that allows for heparin quantification in plasma. This work discusses the effect of the transducing-dye structure and the promise of embedding the sensors in an agarose gel for avoiding red blood cell interference.
How to Cite
R. Nussbaum, K. Robinson, Y. Soda, E. Bakker, Chimia 2022, 76, 284, DOI: 10.2533/chimia.2022.284.
Copyright (c) 2022 Robin Nussbaum, Kye J. Robinson, Yoshiki Soda, Eric Bakker
This work is licensed under a Creative Commons Attribution 4.0 International License.