Expanding the Chemistry Palette for Radiotracer Synthesis

Authors

  • Jennifer Lamb Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Daniel F. Earley Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Amaury Guillou Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Shamisa Behmaneshfar Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Jan Bühler Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Patricia Pires Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Simon Klingler Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Melanie Gut Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Jose Esteban Flores Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Florian Gribi Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Rachael Fay Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Faustine d'Orchymont Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
  • Jason P. Holland Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland;, Email: jason.holland@chem.uzh.ch

DOI:

https://doi.org/10.2533/chimia.2020.946

PMID:

33357287

Keywords:

Antibodies, Bioconjugation, Coordination chemistry, Copper, Density functional theory, Gallium, Graphene, Photochemistry, Positron emission tomography, Protein degradation, Radiochemistry, Zirconium

Abstract

The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic methods and radiochemical tools for building molecular imaging agents with various radionuclides.
CHIMIA Vol. 74 No. 12(2020): Radiochemistry in Switzerland

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Published

2020-12-23

Issue

Vol. 74 No. 12 (2020): Radiochemistry in Switzerland

Section

Scientific Articles

License

Copyright (c) 2020 Jennifer Lamb, Daniel F. Earley, Amaury Guillou, Shamisa Behmaneshfar, Jan Bühler, Patricia Pires, Simon Klingler, Melanie Gut, Jose Esteban Flores, Florian Gribi, Rachael Fay, Faustine d'Orchymont, Jason P. Holland

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
J. Lamb, D. F. Earley, A. Guillou, S. Behmaneshfar, J. Bühler, P. Pires, S. Klingler, M. Gut, J. E. Flores, F. Gribi, R. Fay, F. d'Orchymont, J. P. Holland, Chimia 2020, 74, 946, DOI: 10.2533/chimia.2020.946.