Ynol Ethers: Synthesis and Reactivity

Authors

  • Charlie Verrier Université Grenoble Alpes, Département de Chimie Moléculaire (SERCO), UMR-5250 CNRS, IMCG FR-2607, 38041 Grenoble, France
  • Sébastien Carret Université Grenoble Alpes, Département de Chimie Moléculaire (SERCO), UMR-5250 CNRS, IMCG FR-2607, 38041 Grenoble, France
  • Jean-François Poisson Université Grenoble Alpes, Département de Chimie Moléculaire (SERCO), UMR-5250 CNRS, IMCG FR-2607, 38041 Grenoble, France;, Email: jean-francois.poisson@univ-grenoble-alpes.fr

DOI:

https://doi.org/10.2533/chimia.2016.93

Keywords:

Alkynes, Enol ethers, Ketenes, Synthesis, Ynol ethers

Abstract

Ynol ethers are highly valuable substrates offering a wide range of reactivity. These highly electron-rich heterosubstitued alkynes can be of great synthetic potential. In this mini-review, the different methods for the synthesis of ynol ethers are first presented, divided in three main approaches involving a ?-elimination, a carbene rearrangement and a direct oxidation of an alkyne. Their reactivity is then summarized underlying their synthetic utility. This non-exhaustive review aims at presenting the intrinsic reactivity of these compounds, still underexploited in synthesis.

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Published

2016-02-24

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Section

Scientific Articles

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