Contributions of Biomolecular NMR to Allosteric Drug Discovery

Authors

  • Lukasz Skora Novartis Institutes for Biomedical Research, Novartis Campus, CH-4002 Basel, Switzerland
  • Wolfgang Jahnke Novartis Institutes for Biomedical Research, Novartis Campus, CH-4002 Basel, Switzerland. wolfgang.jahnke@novartis.com

DOI:

https://doi.org/10.2533/chimia.2015.421

Keywords:

Allosteric drug discovery, Biomolecular nmr

Abstract

Drug discovery is a complex process, and a variety of technologies contribute to its success. Biophysical methods have gained widespread attention within the last decade, and in particular NMR spectroscopy as the most versatile biophysical method has seen numerous applications and significant impact to drug discovery. Here we summarize the potential of NMR to support drug discovery, and highlight a number of recent applications.
CHIMIA Vol. 69 No. 07-08(2015): SCS Laureates and Awards & Fall Meeting 2015

Downloads

Published

2015-08-19

Issue

Vol. 69 No. 7-8 (2015): SCS Laureates and Awards & Fall Meeting 2015

Section

Scientific Articles

License

Copyright (c) 2015 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
Chimia 2015, 69, 421, DOI: 10.2533/chimia.2015.421.