An Improved Process for the Preparation of an ?,?-Difluorosulfonylisoxazoline Herbicide
Keywords:Defluorinative silylation, Herbicide, Process chemistry
AbstractAn efficient synthesis of a difluorosulfone-containing herbicide has been achieved by selective reductive silylation of a symmetrical bis(trifluoromethyl)-1,2,3-triazole. Subsequently, a fluoride-induced reaction led to a difluoromethyl anion equivalent, which was reacted with a sulfur electrophile leading ultimately to the key difluorosulfide moiety.
How to Cite
C. Belie, A. Plant, N. Mulholland, M. McLachlan, D. McCormack, A. Longstaff, T. Kozakiewicz, A. Knee, K. Ingram, M. E. Qacemi, M. Diggelmann, J. Dallimore, A. Dalençon, E. Clarke, J. Boehmer, J. Williams, Chimia 2014, 68, 442, DOI: 10.2533/chimia.2014.442.
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