Unique Reactivity of Fluorinated Molecules with Transition Metals

Authors

  • Silvia Catalán Departamento de Química Orgánica Universidad de Valencia E-46100 Burjassot, Spain; Laboratorio de Moléculas Orgánicas Centro de Investigación Príncipe Felipe E-46012, Valencia, Spain
  • Sócrates B. Munoz Loker Hydrocarbon Research Institute Department of Chemistry University of Southern California, Los Angeles CA 90089, USA
  • Santos Fustero Departamento de Química Orgánica Universidad de Valencia E-46100 Burjassot, Spain; Laboratorio de Moléculas Orgánicas Centro de Investigación Príncipe Felipe E-46012, Valencia, Spain. santos.fustero@uv.es

DOI:

https://doi.org/10.2533/chimia.2014.382

Keywords:

Catalysis, Copper, Cross coupling, Fluorine, Gold, Metathesis, Pauson–khand reaction, Silver, Transition metal

Abstract

Organofluorine and organometallic chemistry by themselves constitute two potent areas in organic synthesis. Thus, the combination of both offers many chemical possibilities and represents a powerful tool for the design and development of new synthetic methodologies leading to diverse molecular structures in an efficient manner. Given the importance of the selective introduction of fluorine atoms into organic molecules and the effectiveness of transition metals in C–C and C–heteroatom bond formation, this review represents an interesting read for this aim.

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Published

2014-06-26

Issue

Section

Scientific Articles