Peptide Nucleic Acid – An Opportunity for Bio-Nanotechnology

Philipp Anstaett; Gilles Gasser

doi:10.2533/chimia.2014.264

Peptide Nucleic Acid – An Opportunity for Bio-Nanotechnology

Authors

Philipp Anstaett University of Zurich Department of Chemistry Winterthurerstrasse 190 CH-8057 Zurich, Switzerland
Gilles Gasser University of Zurich Department of Chemistry Winterthurerstrasse 190 CH-8057 Zurich, Switzerland. gilles.gasser@chem.uzh.ch

DOI:

https://doi.org/10.2533/chimia.2014.264

Keywords:

Biotechnology, Nanoparticle, Nanotechnology, Peptide nucleic acid (pna), Sensing

Abstract

DNA is a major player in the field of bio-nanotechnology and many interesting applications have been realized using this oligonucleotide. In contrast, the use of peptide nucleic acid (PNA), which is a non-natural, neutral analogue of DNA with superior hybridization strengths compared to DNA, is still in its infancy in bio-nanotechnology. However, as demonstrated in this short review using selected studies, promising examples demonstrating the tremendous opportunities that PNA can offer for bio-nanotechnology were recently described.