iMatrixSpray: A Free and Open Source Sample Preparation Device for Mass Spectrometric Imaging

Markus Stoeckli; Dieter Staab; Michael Wetzel; Matthias Brechbuehl

doi:10.2533/chimia.2014.146

iMatrixSpray: A Free and Open Source Sample Preparation Device for Mass Spectrometric Imaging

Authors

Markus Stoeckli Novartis Institutes for Biomedical Research, WSJ-155.2.27, Novartis Campus, CH-4056 Basel, Switzerland
Dieter Staab
Michael Wetzel
Matthias Brechbuehl

DOI:

https://doi.org/10.2533/chimia.2014.146

Keywords:

Maldi, Maldi msi, Mass spectrometric imaging, Matrix deposition, Sample preparation

Abstract

A device was built for matrix deposition in mass spectrometric imaging. This spray-type instrument requires no user interaction other than providing the spray solution and selecting the pre-defined or custom-built method. Robustness was achieved by utilizing a delta-robotics design in combination with a simple liquid system. All the information describing the systems is provided as open source and hardware and the design is therefore suitable for wide distribution and adaption by the scientific community.