Comparison of UHPLC-ESI-MS and Hadamard Transform Atmospheric Pressure Ion Mobility-ESI-MS for Rapid Profiling of Isomeric Flavonoids
DOI:
https://doi.org/10.2533/chimia.2014.135Keywords:
Esi-tof-ms, Flavonoids, Glycosides, Ion mobility, UhplcAbstract
Hadamard transform atmospheric pressure ion mobility-MS and rapid UHPLC-MS methods were investigated for analysis of closely related isomeric flavonoids and their glycosides using a test set of seven standards. On a time scale of a few minutes, the flavonoid aglycones were all separated by ion mobility, but not by UHPLC. The glycosides were better resolved by IMS but not completely separated by both methods. The results suggest that IMS provides sufficient resolution for separation of isomeric polyphenols such as flavonoids in high-throughput metabolomics studies.Downloads
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2014-03-26
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Scientific Articles
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Copyright (c) 2014 Swiss Chemical Society
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How to Cite
[1]
M. Groessl, A. Azzollini, P. J. Eugster, B. Plet, J.-L. Wolfender, R. Knochenmuss, Chimia 2014, 68, 135, DOI: 10.2533/chimia.2014.135.