Teaching Enantioselectivity to C–H Bond Functionalizations: Initial Steps of a Rather Long Shot

Authors

  • Nicolai Cramer Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSA, BCH 4305, CH-1015 Lausanne, Switzerland. nicolai.cramer@epfl.ch

DOI:

https://doi.org/10.2533/chimia.2012.869

Keywords:

Asymmetric catalysis, C–h activation, Ligands, Palladium, Rhodium

Abstract

The direct functionalization of non-activated C–H bonds, especially in an enantioselective manner, requires metal catalysts equipped with ligands with specifically designed properties. Examples for asymmetric C(sp2)–H and C(sp3)–H functionalizations using palladium- and rhodium catalysts are shown. This work was rewarded by the 2012 Werner Prize of the Swiss Chemical Society.
CHIMIA Vol. 66 No. 11 (2012): Molecular Sciences' Outreach Activities

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Published

2012-11-26

Issue

Vol. 66 No. 11 (2012): Molecular Sciences' Outreach Activities

Section

Scientific Articles

License

Copyright (c) 2012 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
N. Cramer, Chimia 2012, 66, 869, DOI: 10.2533/chimia.2012.869.