Enzyme-triggered Radical Reactions: Another Approach For Tin-free Radical Chemistry

Authors

  • Ibrahima Cissokho Aix-Marseille Univ, Institut de Chimie Radicalaire UMR 7273, Equipe Chimie Moléculaire Organique, 13397 Cedex 20, Marseille, France
  • Anne-Marie Farnet Aix-Marseille Univ, Institut Méditerranéen de Biodiversité et d'Ecologie UMR CNRS IRD 7263, Equipe Vulnérabilité des Systèmes Microbiens Faculté des Sciences et Techniques de St Jérôme, 13397, Marseille, Cedex 20, France
  • Elisée Ferré Aix-Marseille Univ, Institut Méditerranéen de Biodiversité et d'Ecologie UMR CNRS IRD 7263, Equipe Vulnérabilité des Systèmes Microbiens Faculté des Sciences et Techniques de St Jérôme, 13397, Marseille, Cedex 20, France
  • Michèle P. Bertrand Aix-Marseille Univ, Institut de Chimie Radicalaire UMR 7273, Equipe Chimie Moléculaire Organique, 13397 Cedex 20, Marseille, France
  • Gérard Gil Aix-Marseille Univ, ISM2 UMR 7313, Equipe Chirosciences, 13397 Cedex 20, Marseille, France
  • Stéphane Gastaldi Aix-Marseille Univ, Institut de Chimie Radicalaire UMR 7273, Equipe Chimie Moléculaire Organique, 13397 Cedex 20, Marseille, France

DOI:

https://doi.org/10.2533/chimia.2012.435

Keywords:

1,3-dicarbonyl compounds, Laccase, Oxidoreductase, Radical mediator, Radical reaction

Abstract

The system laccase/mediator/dioxygen is able to trigger radical reactions with radical precursors which are not natural substrates of this enzyme. The radical generation has been accomplished by single electron transfer oxidation of a 1,3-dicarbonyl precursor. The process is exemplified with a radical cascade.
CHIMIA Vol. 66 No. 6 (2012): Organic Free Radicals

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Published

2012-06-27

Issue

Vol. 66 No. 6 (2012): Organic Free Radicals

Section

Scientific Articles

License

Copyright (c) 2012 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
I. Cissokho, A.-M. Farnet, E. Ferré, M. P. Bertrand, G. Gil, S. Gastaldi, Chimia 2012, 66, 435, DOI: 10.2533/chimia.2012.435.