Some Aspects of the Radical Chemistry of Xanthates

Authors

  • Béatrice Quiclet-Sire
  • Samir Z. Zard Ecole Polytechnique, Laboratoire de Synthèse Organique, UMR 7652, 91128 Palaiseau, France

DOI:

https://doi.org/10.2533/chimia.2012.404

Keywords:

Block copolymers, Carbon-carbon formation, Heterocycles, Radical additions, Xanthates

Abstract

Xanthates and related thiocarbonylthio derivatives have proved to be exceedingly useful substrates for both inter- and intra- molecular radical additions. The intermolecular addition to unactivated alkenes, in particular, provides tremendous opportunities for synthesis: various functional groups can be brought together under mild, neutral conditions. Since the adduct is also a xanthate, iteration allows the formation of block polymers through a controlled radical polymerisation (the RAFT/MADIX technology). Also of some importance is the access to highly substituted aromatic and heteroaromatic derivatives.

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Published

2012-06-27

Issue

Section

Scientific Articles