Nanoparticles and Cells: An Interdisciplinary Approach

Authors

  • Alke Petri-Fink Adolphe Merkle Institute University of Fribourg Rte de l'Ancienne Papeterie P. O. Box 209 CH-1723 Marly 1, Switzerland; Chemistry Department University of Fribourg Chemin du Musée 9 CH-1700 Fribourg, Switzerland. alke.fink@unifr.ch
  • Barbara Rothen-Rutishauser Adolphe Merkle Institute University of Fribourg Rte de l'Ancienne Papeterie P. O. Box 209 CH-1723 Marly 1, Switzerland. barbara.rothen@unifr.ch

DOI:

https://doi.org/10.2533/chimia.2012.104

Keywords:

Dendritic cells, Microscopy, Nanoparticles, Particle–cell interaction, Spions

Abstract

In this article we present an overview of some of our research in the field of nanoscience. By combining two different scientific backgrounds (chemistry and biology), we investigate nanoparticle–cell interactions from different angles. This requires an interdisciplinary approach involving material synthesis and characterization, cell biology (biochemistry) and microscopy. In particular, we describe the synthesis and magnetic properties of superparamagnetic iron oxide nanoparticles as well as their behavior in cell culture, evaluate different visualization and detection methods, and investigate the interaction of such magnetic particles with immune cells.

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Published

2012-03-28