Conceptually New Entries into Cells

Authors

  • Javier Montenegro
  • Charlotte Gehin
  • Eun-Kyoung Bang
  • Andrea Fin
  • David Alonso Doval
  • Howard Riezman School of Chemistry and Biochemistry, University of Geneva, CH-1211 Geneva, Switzerland
  • Naomi Sakai
  • Stefan Matile School of Chemistry and Biochemistry, University of Geneva, CH-1211 Geneva, Switzerland. stefan.matile@unige.ch

DOI:

https://doi.org/10.2533/chimia.2011.853

Keywords:

Cell-penetrating peptides, Cellular uptake, Sensing, Sirna, Transport

Abstract

This article summarizes the background and a few preliminary results concerning project 7 of the NCCR Chemical Biology. The general objective is to explore new concepts for cellular uptake, membrane tunneling, sensing and labeling. Emphasis is on the use of dynamic covalent chemistry for counterion activation, slow release of polyions and fluorescent probes, and the generation of activator libraries and polyions that grow and shrink.
CHIMIA Vol. 65 No. 11 (2011): NCCR Chemical Biology

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Published

2011-11-23

Issue

Vol. 65 No. 11 (2011): NCCR Chemical Biology

Section

Scientific Articles

License

Copyright (c) 2011 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
J. Montenegro, C. Gehin, E.-K. Bang, A. Fin, D. A. Doval, H. Riezman, N. Sakai, S. Matile, Chimia 2011, 65, 853, DOI: 10.2533/chimia.2011.853.