Chemical Biology Approaches to Membrane Homeostasis and Function

Authors

  • Miwa Takahashi-Umebayashi Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • Kai Johnsson Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
  • Luc Reymond Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
  • Aurélien Roux Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
  • Robbie Loewith Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • Gerardo Turcatti Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
  • Christian Heinis Institute of Chemical Sciences and Engineering, Life Sciences, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
  • Stefan Matile Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • David Alonso Doval Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • Andreas Zumbuehl Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • Thomas Hannich Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • Ludovic Pineau Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland
  • Howard Riezman Departments of Biochemistry, Organic Chemistry and Molecular Biology, University of Geneva, 30 quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland. Howard.Riezman@unige.ch

DOI:

https://doi.org/10.2533/chimia.2011.849

Keywords:

Chemical biology, Fluorescent dyes, Giant unilamellar vesicles, Insulin receptor, Membranes, Microdomains, Rafts, Signaling, Sphingolipids, Sterols

Abstract

The study of membranes is at a turning point. New theories about membrane structure and function have recently been proposed, however, new technologies, combining chemical, physical, and biochemical approaches are necessary to test these hypotheses. In particular, the NCCR in chemical biology aims to visualize and characterize membrane microdomains and determine their function during hormone signaling.
CHIMIA Vol. 65 No. 11 (2011): NCCR Chemical Biology

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Published

2011-11-23

Issue

Vol. 65 No. 11 (2011): NCCR Chemical Biology

Section

Scientific Articles

License

Copyright (c) 2011 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
M. Takahashi-Umebayashi, K. Johnsson, L. Reymond, A. Roux, R. Loewith, G. Turcatti, C. Heinis, S. Matile, D. A. Doval, A. Zumbuehl, T. Hannich, L. Pineau, H. Riezman, Chimia 2011, 65, 849, DOI: 10.2533/chimia.2011.849.