Syntheses and Biological Activities of 1,4-Iminoalditol Derivatives as ?-L-Fucosidase Inhibitors

Authors

  • Elena Moreno-Clavijo Dept. Organic Chemistry Faculty of Chemistry University of Seville P. O. Box 1203, E-41071 Seville, Spain
  • Ana T. Carmona Dept. Organic Chemistry Faculty of Chemistry University of Seville P. O. Box 1203, E-41071 Seville, Spain;, Email: anatere@us.es
  • Antonio J. Moreno-Vargas Dept. Organic Chemistry Faculty of Chemistry University of Seville P. O. Box 1203, E-41071 Seville, Spain
  • Lidia Molina Dept. Organic Chemistry Faculty of Chemistry University of Seville P. O. Box 1203, E-41071 Seville, Spain
  • Inmaculada Robina Dept. Organic Chemistry Faculty of Chemistry University of Seville P. O. Box 1203, E-41071 Seville, Spain;, Email: robina@us.es

DOI:

https://doi.org/10.2533/chimia.2011.40

Keywords:

Fucosidases, Glycosidase inhibitors, Iminosugars, Pyrrolidines

Abstract

A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of ?-L-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.

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Published

2011-02-23

Issue

Section

Scientific Articles

How to Cite

[1]
E. Moreno-Clavijo, A. T. Carmona, A. J. Moreno-Vargas, L. Molina, I. Robina, Chimia 2011, 65, 40, DOI: 10.2533/chimia.2011.40.