An Efficient Entry to Planar Chiral Organometallic Complexes via Pd-Catalyzed Asymmetric Hydrogenolysis

Authors

  • Audrey Mercier
  • Wee Chuan Yeo
  • Xavier Urbaneja
  • E. Peter Kündig University of Geneva, Department of Organic Chemistry, 30 Quai Ernest Ansermet, CH-1211 Geneva 4

DOI:

https://doi.org/10.2533/chimia.2010.177

Keywords:

Catalytic desymmetrization, Chromium, Hydrogenolysis, Planar chirality, Ruthenium

Abstract

Planar chiral chromium- and ruthenium-based arene complexes were prepared with high levels of enantioselectivity via a Pd-catalyzed asymmetric hydrogenolysis reaction using a bulky chiral phosphoramidite ligand. Key elements for the efficiency of the process are the use of DABCO as borane-trapping reagent as well as substantial kinetic resolution, which was found to enhance the stereochemical outcome of the reaction.
CHIMIA Vol. 64 No. 3 (2010): Laureates: Awards and Honors, SCS Fall Meeting 2009

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Published

2010-03-31

Issue

Vol. 64 No. 3 (2010): Laureates: Awards and Honors, SCS Fall Meeting 2009

Section

Scientific Articles

License

Copyright (c) 2010 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
A. Mercier, W. C. Yeo, X. Urbaneja, E. P. Kündig, Chimia 2010, 64, 177, DOI: 10.2533/chimia.2010.177.