(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis

Authors

  • Deborah A. Longbottom
  • Vilius Franckevičius
  • Steven V. Ley

DOI:

https://doi.org/10.2533/chimia.2007.247

Keywords:

Asymmetric, Organocatalysis, Proline, Synthesis, Tetrazole

Abstract

This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of each reaction type for which they have proved to be efficient catalytic species. Where relevant, a comparison is made with other organocatalysts in similar asymmetric reaction processes.

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Published

2007-05-30

Issue

Section

Scientific Articles

How to Cite

[1]
D. A. Longbottom, V. Franckevičius, S. V. Ley, Chimia 2007, 61, 247, DOI: 10.2533/chimia.2007.247.