Process Development for Active Pharmaceutical Ingredients Following a Developmental Cascade

Authors

  • Carmen Adler
  • Jürg Brunner
  • Claudia Fichtner
  • Peter Küng
  • Michael K. Levis
  • Hans-Rudolf Ruchti
  • Anders Sjöberg
  • Beat Weber

DOI:

https://doi.org/10.2533/chimia.2006.523

Keywords:

Api, Developmental cascade, Drug substance, Process development

Abstract

The developmental process for drug substances, as carried out in a medium-sized company is described. A cascade approach, ranging from route selection to commercial production and the corresponding intermediate steps, is discussed. A concerted teamwork is essential for optimal results, and the roles and activities of the team members are outlined.

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Published

2006-09-01

Issue

Section

Scientific Articles

How to Cite

[1]
C. Adler, J. Brunner, C. Fichtner, P. Küng, M. K. Levis, H.-R. Ruchti, A. Sjöberg, B. Weber, Chimia 2006, 60, 523, DOI: 10.2533/chimia.2006.523.