Intramolecular Schmidt Reaction: Applications in Natural Product Synthesis

Authors

  • Erich Nyfeler
  • Philippe Renaud

DOI:

https://doi.org/10.2533/000942906777674714

Keywords:

Alkaloids, Alkyl azides, Iminium ions, Lactams, Rearrangement, Tertiary amines, Total synthesis

Abstract

The intramolecular Schmidt reaction was first described at the beginning of the 1990s and rapidly proved to be a powerful tool for the fast assembly of complex nitrogen-containing heterocycles. This review focuses on the application of this reaction in the synthesis of natural products and other biologically relevant compounds.

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Published

2006-05-24

Issue

Vol. 60 No. 5 (2006): Hot Topics: Multifunctional Materials and Organic Synthesis

Section

Scientific Articles

License

Copyright (c) 2006 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
E. Nyfeler, P. Renaud, Chimia 2006, 60, 276, DOI: 10.2533/000942906777674714.