Albert Hofmann's Pioneering Work on Ergot Alkaloids and Its Impact on the Search of Novel Drugs at Sandoz, a Predecessor Company of Novartis: Dedicated to Dr. Albert Hofmann on the occasion of his 100th birthday

Authors

  • Rudolf K.A. Giger
  • Günter Engel

DOI:

https://doi.org/10.2533/000942906777675164

Keywords:

Aminocyclole, Bromocriptine parlodel reg, Dihydroergotamine dihydergot reg, Dihydro ergot peptide alkaloids, Ergobasin/ergometrin, Ergocornine, Ergocristine, Alpha- and beta-ergocryptine, Ergolene, Ergoline, Ergoloid mesylate hydergine reg, Ergotamine gynergen reg, Ergotoxine, Lisuride, Lysergic acid diethylamide lsd, Methylergometrine methergine reg, Methysergide deseril reg, Paspalic acid, Pindolol visken reg, Psilocybin, Serotonin, Tegaserod zelmac reg/zelnorm reg, Tropisetron navoban reg

Abstract

The scientific research on ergot alkaloids is fundamentally related to the work of Dr. Albert Hofmann, who was able to produce, from 1935 onwards, a number of novel and valuable drugs, some of which are still in use today. The complex chemical structures of ergot peptide alkaloids and their pluripotent pharmacological activity were a great challenge for Dr. Hofmann and his associates who sought to unravel the secrets of the ergot peptide alkaloids; a source of inspiration for the design of novel, selective and valuable medicines.

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Published

2006-02-23

Issue

Vol. 60 No. 1-2 (2006): Pharmaceutical Sciences at Uni Basel

Section

Scientific Articles

License

Copyright (c) 2006 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
R. K. Giger, G. Engel, Chimia 2006, 60, 83, DOI: 10.2533/000942906777675164.