Alkylation of Ethyl Pyruvate via Reductive Coupling of Alkenes and Ethyl 2-(Benzenesulfonylamino)acrylate
DOI:
https://doi.org/10.2533/000942905777676722Keywords:
Alkylation, Enamides, Hydroboration, Organoboranes, Radical reactions, SulfonamidesAbstract
Radical coupling of B-alkylcatecholboranes, in situ generated from the corresponding alkenes, with ethyl 2-(benzenesulfonylamino)acrylate is reported. This reaction represents an extension of the radical allylation of Balkylcatecholboranes by allylsulfones. This unique process allows the preparation of various ?-ketoesters (alkylated pyruvates) in a straightforward manner. It also demonstrates the generality of the radical mediated C–C bond formation starting from organoboranes and allylic benzenesulfonyl derivatives.Downloads
Published
2005-03-01
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Scientific Articles
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Copyright (c) 2005 Swiss Chemical Society
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How to Cite
[1]
V. Darmency, P. Renaud, Chimia 2005, 59, 109, DOI: 10.2533/000942905777676722.