Synthesis and Biological Properties of Novel Fluoroprostaglandin Derivatives: Highly Selective and Potent Agonists for Prostaglandin Receptors

Authors

  • Yasushi Matsumuraa
  • Takashi Nakanob
  • Nobuaki Moria
  • Yoshitomi Morizawab

DOI:

https://doi.org/10.2533/000942904777678073

Keywords:

Antiplatelet, Fluorination, Glaucoma, Prostaglandin, Receptor

Abstract

Synthesis of novel 7,7-difluoroprostacyclin and 15-deoxy-15,15-difluoro-PGF2? derivatives will be presented. These compounds show high affinity to prostaglandin receptors and potent biological activities.

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Published

2004-03-01

Issue

Vol. 58 No. 3 (2004): Fluorine in the Life Science Industry

Section

Scientific Articles

License

Copyright (c) 2004 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
Y. Matsumuraa, T. Nakanob, N. Moria, Y. Morizawab, Chimia 2004, 58, 148, DOI: 10.2533/000942904777678073.