Physical and Molecular Properties of Agrochemicals: An Analysis of Screen Inputs, Hits, Leads, and Products
DOI:
https://doi.org/10.2533/000942903777678641Keywords:
Agrochemicals, Bioavailability, Design guidelines, Property profiles, 'rule of five'Abstract
This work provides a comprehensive overview of agrochemical properties in terms of the way they change during progression from screen hit to product and in terms of their limits as expressed in modern commercial products. Most herbicides and fungicides readily meet the Lipinski 'rule of five' criteria for drug-like compounds with many meeting the more constrained limits reported for pharmaceutical leads.Downloads
Published
2003-11-01
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Section
Scientific Articles
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Copyright (c) 2003 Swiss Chemical Society
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How to Cite
[1]
E. D. Clarke, J. S. Delaney, Chimia 2003, 57, 731, DOI: 10.2533/000942903777678641.