Microarrays and Surface Engineering for Bioanalysis

Authors

  • Hui Gao
  • Sylvie Guinchard
  • François Crevoisier
  • Silvia Angeloni
  • Hans Sigrist

DOI:

https://doi.org/10.2533/000942903777678731

Keywords:

Functional platform, Microarray, Photoimmobilization, Proteomics, Surface passivation

Abstract

Molecular engineering and covalent immobilization of biomolecules on material surfaces whilst retaining specificity and biological functions is a major challenge in bioarray manufacturing and analysis. Photochemical functionalization of materials enables specific bioengineering and facile manufacturing of biotech products for microanalysis with concomitant surface passivation. Surfaces engineered with polysaccharides render materials hydrophilic, biocompatible and generally applicable for probe molecule immobilization. Products and procedures described support microanalytical investigations in all '-omics' domains.

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Published

2003-10-01

Issue

Section

Scientific Articles