Catalytic Rigid-Rod ?-Barrels with Hydrazide Cofactors to Convert Poor Substrates as Hydrazone Conjugates

Authors

  • Abhigyan Som
  • Pinaki Talukdar
  • Bodo Baumeister
  • Stefan Matile

DOI:

https://doi.org/10.2533/000942903777679541

Keywords:

Beta-barrels, Bioorganic chemistry, Enzyme mimics, Ion channels, Molecular recognition

Abstract

The usefulness of pyrene-1,3,6-trisulfonates as cofactors for p-octiphenyl ?-barrel ion channels to mediate recognition and conversion of otherwise inaccessible benzaldehyde substrates is described.

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Published

2003-04-01