Bioorganic Chemistry of Rigid-Rod Molecules: Adventures with p-Oligophenyls

Authors

  • Yoann Baudry
  • Bodo Baumeister
  • Gopal Das
  • David Gerard
  • Stefan Matile
  • Naomi Sakai
  • Abhigyan Som
  • Nathalie Sordé
  • Pinaki Talukdar

DOI:

https://doi.org/10.2533/000942902777679948

Keywords:

Antibiotics, Beta-barrels, Enzyme mimics, Ion channels, Molecular recognition, Sensors

Abstract

Studies on the usefulness of rigid-rod molecules to address pertinent questions of biological relevance are summarized. Emphasis is placed on (a) the supramolecular functional plasticity of p-octiphenyl ?-barrels expressed in molecular recognition (adaptable synthetic hosts), molecular translocation (adaptable synthetic ion channels) and molecular transformation (esterases, RNases), (b) molecular recognition of polarized membranes by rigid push-pull rods, as well as (c) the synthetic organic chemistry of rigid-rod molecules.

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Published

2002-12-01

Issue

Vol. 56 No. 12 (2002): Chemistry at the University of Geneva

Section

Scientific Articles

License

Copyright (c) 2002 Swiss Chemical Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

[1]
Y. Baudry, B. Baumeister, G. Das, D. Gerard, S. Matile, N. Sakai, A. Som, N. Sordé, P. Talukdar, Chimia 2002, 56, 667, DOI: 10.2533/000942902777679948.