'Never Mind a Barrel'

Authors

  • Bodo Baumeister
  • Gopal Das
  • Naomi Sakai
  • Stefan Matile Department of Organic Chemistry, University of Geneva, CH-1211 Geneva

DOI:

https://doi.org/10.2533/chimia.2001.302

Keywords:

Protein mimetics, Rigid-rod molecules, Supramolecular chemistry, Tertiary structure

Abstract

The general usefulness of rigid-rod molecules rather than ?-sheets as molecular staves for the construction of artificial ?-barrels with preserved structural and functional plasticity is described. Aspects of the structural plasticity of rigid-rod ?-barrels are elaborated in more detail with respect to barrel truncation, elongation, contraction and expansion in water and/or bilayer membranes.

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Published

2001-04-25