Radicals and the Birth and Death of DNA

Authors

  • Bernd Giese

DOI:

https://doi.org/10.2533/chimia.2001.275

Keywords:

Bleomycin, Dna, Enzymes, Radicals, Ribonucleotide reductase

Abstract

Radicals have important functions in the enzymatic synthesis of deoxyribonucleotides and their destruction by antibiotics. The chemical basis for these reactions is that radicals dramatically speed up ionic reactions. Nature has developed methods to generate these radicals under mild conditions in water as solvent. The 'catalytic' effect of these reactive intermediates is described.

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Published

2001-04-25

How to Cite

[1]
B. Giese, Chimia 2001, 55, 275, DOI: 10.2533/chimia.2001.275.