Excursions of Synthetic Organic Chemists to the World of Oligomers and Polymers

Authors

  • Dieter Seebach
  • Albert K. Beck
  • Magnus Rueping
  • Jürg V. Schreiber
  • Holger Sellner

DOI:

https://doi.org/10.2533/chimia.2001.98

Keywords:

Dendritic cross-linkers, Oligo-(3-hydroxybutanoates), Beta-peptides, Polymer-bound chiralligands, Secondary structures

Abstract

The activities of a group devoted to organic synthesis in the field of polymer and oligomer chemistry have led to new types of dendritic cross-linking compounds for the polymerization of styrene to give high-quality materials. In addition the synthesis of uniform ('monodisperse'), high-molecular weight oligomers of 3-hydroxybutanoic acid provided samples for investigations to prove the hypothesis that polyhydroxybutyrates are natural ion-channel components in living organisms. Oligomers of ?-amino acids were prepared and have been shown to form all the secondary structures known from natural peptides and proteins (composed of ?-amino acids), i.e. helices, pleated sheets, turns, hair pins and stacks with properties differing fundamentally from those of the natural analogs.

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Published

2001-03-28

Issue

Section

Scientific Articles

How to Cite

[1]
D. Seebach, A. K. Beck, M. Rueping, J. V. Schreiber, H. Sellner, Chimia 2001, 55, 98, DOI: 10.2533/chimia.2001.98.