On-line Festphasenextraktion (SPE) für die HPLC

On-line Solid Phase Extraction for LC Analysis

Abstract

Solid Phase Extraction (SPE) has rapidly evolved to become one of the most popular methods for sample clean-up today. Based on well-known chromatographic principles, SPE is easily performed, typically provides superior results, and will continue to replace traditional extraction techniques. SPE can be automated using robotic type sample processors; however, for SPE followed by LC or LC/MS, there is a much more efficient alternative and offers ruggedness, excellent precision and high sample throughput. With the PROSPEKT-System, the purified analytes elute directly from the SPE column onto the analytical column for LC analysis, eliminating off-line sample transfer including eluate collection, evaporation, reconstituation and injection.