Photochemical Transformations of Proteinogenic and Non-Proteinogenic Amino Acids

Authors

  • Axel G. Griesbeck

DOI:

https://doi.org/10.2533/chimia.1998.272

Abstract

The photochemistry of N-activated enantiomerically pure α-amino acids is described with emphasis on chemo-, regio-, stereo-, and spin selectivity. An especially valuable chromophore is the phthalimido group. The first excited singlet states are short-lived and deactivated (chemically) via homolytic CH cleavage or (physically) via electron-transfer steps. The first excited triplet states are chemically deactivated via electron-transfer reactions and subsequent deprotonation/coupling steps. A wide variety of product types were synthesized, and potential target molecules were available by tuning the reaction conditions. Also remote groups can be activated by means of electron-transfer steps, which represents an attractive new synthetic protocol for macrocyclization.

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Published

1998-06-24

How to Cite

[1]
A. G. Griesbeck, Chimia 1998, 52, 272, DOI: 10.2533/chimia.1998.272.