Desymmetrisation of Dienylsilanes. Stereoselective Access to Cyclitols and Carba-Sugars

Authors

  • Yannick Landais

DOI:

https://doi.org/10.2533/chimia.1998.104

Abstract

The diastereo- and enantioselective functionalisation of 1,4-cyclohexadienylsilanes using Sharpless asymmetric dihydroxylation and aminohydroxylation offers a straightforward access to various classes of potent inhibitors of glycosidases. The scope and limitation of this desymmetrisation method is illustrated here with the synthesis of various conduritols, carba-sugars and carba-C-disaccharides.

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Published

1998-03-25

How to Cite

[1]
Y. Landais, Chimia 1998, 52, 104, DOI: 10.2533/chimia.1998.104.

Issue

Section

Scientific Articles