Organic Synthesis with α-Silylcarbonyl Compounds

Abstract

Our interest in organosilicon compounds has led us to examine the chemistry of rarely used α-silylcarbonyl compounds. Possible applications of these synthons are not covered totally here, but a few examples along these lines should demonstrate the utility of these structurally simple substrates in organic synthesis. The preparation of the α-silyl esters and some examples of their stereocontrolled conversion into polysubstituted tetrahydrofurans is presented.