Consideration of Solid-Phase Synthesis with Reference to Quinolone Antibiotics

Authors

  • Alasdair A. Macdonald
  • Sheila H. DeWitt
  • Robert Ramageu

DOI:

https://doi.org/10.2533/chimia.1996.266

Abstract

The general utility of solid-phase synthesis for creating libraries of compounds will be discussed with particular reference paid to the development of a solid-phase organic synthetic route to quinolones. Using the DIVERSOMER® technology a library of quinolones have been prepared, purified and analyzed. Additionally, the issue of resin impurities and by-products will be discussed.

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Published

1996-06-26

Issue

Section

Scientific Articles